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General Chemistry ›› 2022, Vol. 8 ›› Issue (3-4): 220009-220009.DOI: 10.21127/yaoyigc20220009

• Perspectives • Previous Articles    

Synthesis of Regioselective Carbohydrates Building Blocks by Heterogeneous Engineered Biocatalysts

Jose M. Palomo*   

  1. Instituto de Catálisisy Petroleoquímica (ICP), CSIC. C/Marie Curie 2. 28049 Madrid, Spain
  • Received:2022-11-12 Accepted:2022-11-30 Online:2022-12-30 Published:2022-12-21
  • Contact: Email: josempalomo@icp.csic.es (J. M. P.)

Abstract: Regioselective synthesis of carbohydrate building blocks by the application of biocatalytic approaches represents a convenient and sustainable way for the production of pharmaceuticals. The enormous potential of enzymes for the transformation of synthetic chemicals with high regioselectivity is on increasing awareness. This perspective focuses on showing some of the advances on the use of lipases engineering as immobilized catalyst for regioselective deprotection processes for potential industrial production glycoderivatives building blocks.

Key words: carbohydrate, biocatalysis, lipases, glycoderivatives, protein engineering, heterogeneous catalysis

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