Progress of Liposomal Nanohybrid Cerasomes as Novel Drug Nanocarriers

doi:10.21127/yaoyigc20170013

Abstract

Abstract:

Despite many benefits, liposomes have still not realized their full potential as vehicles for drug delivery due to the morphological instability. Recently, liposomal nanohybrid cerasomes have been developed as novel drug nanocarriers based on organoalkoxysilane through a sol-gel reaction in combination with self-assembly process. The presence of polyorganosiloxane network on the surface imparts cerasomes higher morphological stability than conventional liposomes and the incorporation of liposomal bilayer structure into cerasomes boosts the biocompatibility in comparision with silica nanoparticles with similar size. Moreover, cerasomes are able to encapsulate various drug molecules and exhibit controlled drug release profile. In addition, cerasomes are easy to be conjugated with biomolecules through silane-coupler chemistry due to the silanols on the surface. Therefore, cerasomes are expected to be ideal drug delivery systems owning to the unique advantages. The present paper will briefly introduce the preparation and properties of cerasomes, followed by reviewing the progress of cerasomes for drug delivery.

Key words: cerasomes, cerasome-forming lipids, preparation, properties, drug delivery

Shihao Li, Jie Jiang, Shanshan Zhu, Yinan Yan, Gang Huang, Dannong He. Progress of Liposomal Nanohybrid Cerasomes as Novel Drug Nanocarriers[J]. General Chemistry, 2017, 3(4): 194-201.

References

1	Kessler D. A.; Austin R. H.; Levine H. Cancer Res.2014, 74, 4663.
2	Allen T. M.; Cullis P. R. Science 2004, 303, 1818.
3	Bamrungsap S.; Zhao Z.; Chen T.; Wang L.; Li C.; Fu T.; Tan W. Nanomedicine 2012, 7, 1253.
4	Bonifácio B. V.; Silva P. B. D.; Negri K. M. S.; Bauab T. M.; Chorilli, M. Int. J. Nanomed. 2014, 9, 1.
5	Kingsley J. D.; Dou H.; Morehead J.; Rabinow B.; Gendelman H. E.; Destache, C. J. J. Neuroimmune Pharm.2006, 1, 340.
6	Tiwari G.; Tiwari R.; Sriwastawa B.; Bhati L.; Pandey S.; Pandey P.; Bannerjee, S. K. Int. J. Pharm. Investig. 2012, 2, 2.
7	Seleci M.; Ag S. D.; Scheper T.; Stahl, F. Int. J. Mol. Sci.2017, 18, 7.
8	Zhang Y.; Zhai M.; Chen Z.; Han X.; Yu F.; Li Z.; Xie X.; Han C.; Yu L.; Yang Y. Drug Deliv. 2017, 24, 1045.
9	Li S.; Goins B.; Zhang L.; Bao A. Bioconjugate Chem. 2015, 23, 1322.
10	Jing-Hai M. U.; Zhou Y. E.; Zhang Q.; Yin J. Curr. Biotechnol. 2016, 6, 179.
11	Anna W.; Juergen B. Nanomaterials 2017, 7, 189.
12	Salonen J.; Kaukonen A. M.; Hirvonen J.; Lehto V. P. J. Pharm. Sci.2008, 97, 632.
13	Zhao H.; Duong H. H. P.; Yung, L. Y. L. Macromol. Rapid Commun. 2010, 31, 1163.
14	Kamimura M.; Nagasaki, Y. J. Photopolym. Sci. Technol.2013, 26, 161.
15	Biswas S.; Kumari P.; Lakhani P. M.; Ghosh B. Eur. J. Pharm. Sci. 2016, 83, 184.
16	Pal K.; Banthia A. K.; Majumdar, D. K. J. Mater. Sci.: Mater. Med.2014, 25, 2215.
17	Bastiancich C.; Danhier P.; Préat V.; Danhier, F. J. Control. Release 2016, 243, 29.
18	Lasic D. D. J. Control. Release 1997, 48, 203.
19	Lee S. M.; Chen H.; Dettmer C. M.; O'Halloran T. V.; Nguyen, S. T. J. Am. Chem. Soc. 2007, 129, 15096.
20	Leung S. L.; Zha Z. B.; Teng W. B.; Cohn C.; Dai Z. F.; Wu, X. Y. Soft Matter 2012, 8, 5756.
21	Katagiri K.; Ariga K.; Kikuchi J. I. Cheminform 1999, 30, 661.
22	Hashizume M.; Kawanami S. I.; Iwamoto S.; Isomoto T.; Kikuchi, J. I. Thin Solid Films 2003, 438, 20.
23	Liang X. L.; Li X. D.; Jing L. J.; Xue P.; Jiang L. D.; Ren Q. S.; Dai Z. F. Chemistry 2013, 19, 16113.
24	Katagiri K.; Hamasaki R.; Ariga K.; Kikuchi, J. I. J. Sol-Gel Sci. Technol.2003, 26, 393.
25	Kikuchi J. I.; Yasuhara K. Adv. Biomimetics 2011, 2, 232.
26	Wang Y.; Chen Y.; Zhang M. Z.; Qu H.; Zheng J.; Pang Q.; Yan X. RSC Adv. 2016, 6, 16292.
27	Cao Z.; Ma Y.; Yue X. L.; Li S.; Dai Z. F.; Kikuchi J. Chem. Commun. 2010, 46, 5265.
28	Jin Y. S.; Yue X. L.; Zhang Q. Y.; Wu X.; Cao Z.; Dai, Z. F. Acta Biomater.2012, 8, 3372.
29	Katagiri K.; Hashizume M.; Ariga K.; Terashima T.; Kikuchi J. Chemistry 2007, 13, 5272.
30	Li S.; Ma Y.; Yue X.; Cao Z.; Liu S.; Dai, Z. J. Disper. Sci. Technol. 2010, 31, 1727.
31	Zhang C. Y.; Cao Z.; Zhu W. J.; Liu J.; Jiang Q.; Shuai, X. T. Colloids Surface B 2014, 116, 327.
32	Cao Z.; Yue X. L.; Jin Y. S.; Wu X.; Dai Z. F. Colloids Surface B 2012,98, 97.
33	Cao Z. Ph.D. Dissertation, Harbin Institute of Technology, Harbin, 2011 (in Chinese).
34	Ma Y.; Dai Z. F.; Gao Y. G.; Cao Z.; Zha Z.; Yue X.; Kikuchi J. Nanotoxicology 2011, 5, 622.
35	Ma Y.; Dai Z. F.; Zha Z. B.; Gao Y.; Yue X. Biomaterials 2011, 32, 9300.
36	Liang X. L.; Li X. D.; Jing L. J.; Xue P.; Jiang L.; Ren Q.; Dai Z. F. Chemistry 2013, 19, 16113.
37	Liang X. L.; Gao J.; Jiang L. D.; Luo J.; Jing L.; Li X.; Jin Y.; Dai, Z. F. ACS Nano 2015, 9, 1280.
38	Su Q.; Pu X.; Bai H.; Chen X.; Liao X.; Huang Z.; Yin, G. Curr. Drug Deliv.2017, 14, 1567.
39	Liang X. L.; Yue X. L.; Dai Z. F.; Kikuchi J. Chem. Commun. 2011, 47, 4751.
40	Liang X. L.; Li X.; Yue X.; Dai, Z. F. Angew. Chem., Int. Ed.2011, 50, 11622.
41	Zhou G.; Li L.; Xing J.; Jalde S.; Li Y.; Cai J.; Chen J.; Liu P.; Gu N.; Ji M. Colloids Surface B.2016, 148, 518.
42	Cao Z.; Zhu W. J.; Wang W.; Zhang C.; Xu M.; Liu J.; Feng S. T.; Jiang Q.; Xie, X. Int. J. Nanomed.2014, 9, 5103.
43	Jin Y. S.; Li Y. Y.; Pan H. J.; Dai, Z. F. RSC Adv.2014, 4, 42808.
44	Wang Y. F.; Wang B. B.; Liao H.; Song X.; Wu H.; Wang H.; Shen H.; Ma X.; Tan, M. J. Mater. Chem. B 2015, 3, 7291.
45	Leung S. L.; Zha Z.; Cohn C.; Dai Z. F.; Wu, X. Colloids Surface B 2014, 121, 141.
46	Minamida D.; Okada S.; Hashizume M.; Sasaki Y.; Kikuchi J.-i.; Hosoito N.; Imori, T. J. Sol-Gel Sci. Technol.2008, 48, 95.
47	Ma Y.; Liang X. L.; Tong S.; Bao G.; Ren Q. S.; Dai, Z. F. Adv. Funct. Mater.2013, 23, 815.
48	Jing L. J.; Shi J. Y.; Fan D.; Li Y.; Liu R.; Dai Z.; Wang F.; Tian, J. ACS Appl. Mater. Interfaces 2015, 7, 22095.
49	Liang X. L.; Li X. D.; Yue X. L.; Dai, Z. F. Angew. Chem., Int. Ed. Engl.2011, 50, 11622.
50	Yasuhara K.; Miki S.; Nakazono H.; Ohta A.; Kikuchi J. Chem. Commun. 2011, 47, 4691.
51	Yasuhara K.; Hayashi H.; Jun-Ichi K. Chem. Lett. 2012, 41, 1223.
52	Lin L.; Wang X.; Guo Y.; Ren K.; Li X.; Jing L.; Yue X.; Zhang Q.; Dai Z. RSC Adv. 2016, 6.
53	Rodríguez G.; Barbosabarros L.; Rubio L.; Cócera M.; Lópeziglesias C.; De l. M. A.; López, O. Colloids Surfaces B 2011, 84, 390.
54	Barua S.; Yoo J. W.; Kolhar P.; Wakankar A.; Gokarn Y. R.; Mitragotri, S. P. Natl. Acad. Sci. USA 2013, 110, 3270.
55	Zhang W.; Sun J.; Liu Y.; Tao M.; Ai X.; Su X.; Cai C.; Tang Y.; Feng Z.; Yan X. Mol. Pharm. 2014, 11, 3279.
56	Doshi N.; Prabhakarpandian B.; Rea-Ramsey, A.; Pant, K.; Sundaram, S.; Mitragotri, S.J. Control. Release 2010, 146, 196.
57	Adriani G.; Tullio M. D. D.; Ferrari M.; Hussain F.; Pascazio G.; Liu X.; Decuzzi P. Biomaterials 2012, 33, 5504.
58	Li L.; Liang X.; Xu Y.; Yang Y.; Li X.; Dai Z. Bioconjugate Chem. 2017, 28, 2410.
59	Lin L.; Wang X.; Li X.; Yang Y.; Yue X.; Zhang Q.; Dai Z. Bioconjugate Chem. 2016, 28, 53.

[1]	Yuancheng Ji and Junqiu Liu. Hollow Polymer Capsules for Drug Delivery [J]. General Chemistry, 2021, 7(1): 200009-200009.
[2]	B. K. Pandey, A. K. Shukla, R. K. Kotanala, J. Shah, and R. Gopala. Optical and Magnetic Properties of Superparamagnetic Fe₃O₄ Colloidal Nanoparticles [J]. General Chemistry, 2020, 6(4): 200006-200006.
[3]	Samia Benmansour, Carlos J. Gómez-García. Heterometallic Anilato-Based Layered Magnets [J]. General Chemistry, 2020, 6(1): 190033-190033.
[4]	Thalía Jiménez, C. I. León-Pimentel, Diego Seuret-Jiménez, Maykel Courel. State of the Art on Sb₂(S_1-_x, Se_x)₃ Thin Film Solar Cells [J]. General Chemistry, 2019, 5(2): 180029-180029.
[5]	Maykel Courel, A. Arce-Plaza, D. O. Oseguera-Galindo, O. Vigil-Galan. The Path to Improve Kesterite Solar Cell Efficiency [J]. General Chemistry, 2018, 4(4): 180015-.
[6]	Ming Sun, Jinjin Tie, Yao Li, Lin Yu. NiCo₂S₄-Based Materials for Electrochemical Applications [J]. General Chemistry, 2017, 3(4): 202-206.
[7]	Yiwen Fang, Xupeng Lu, Wenbin Chen. Application of Nano-TiO₂ in Cosmetics [J]. General Chemistry, 2017, 3(2): 125-129.
[8]	Yuyu Liu, Lei Yang, Xiaofei Zhang, Jiewei Li, Linghai Xie, Mingdong Yi, Wei Huang. Theoretical Study of σ-π Conjugated Semiconductors Based on cis- and trans-Cyclopropane Derivatives [J]. General Chemistry, 2015, 1(1): 8-14.