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General Chemistry

Special Issue: 2D Materials

• Perspective • Previous Articles     Next Articles

Hollow Polymer Capsules for Drug Delivery

Yuancheng Jia and Junqiu Liu*,a,b   

  1. a State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun, Jilin 130012, China
    b College of Material, Chemistry and Chemical Engineering, Hangzhou Normal University, Hangzhou, Zhejiang 311121 China
  • Received:2020-05-16 Revised:2020-06-16 Online:2021-03-29 Published:2021-03-29
  • Contact: junqiuliu@jlu.edu.cn (J. L.)
  • Supported by:
    This work was supported by the National Key R&D Program of China (Grant No. 2018YFA0901600).

Abstract: Hollow polymer capsules (HPC) are one of the widely studied topics in two-dimensional (2D) materials as ar-tificial cargo carriers that simulate natural cells containing life substances and complex life activities, In the past two decades, methodologies and application scenarios for the synthesis of polymer capsules with diversified morphology and multiple functions have received extensive attention. In particular, well-defined HPC with hollow compartments can serve as a drug delivery system with high load capacity, low toxicity, targeted and efficient release. This perspective aims to briefly summarize the developed fabrication strategy of HPC, evaluate their application characteristics in drug encapsulation and delivery, and propose a development direction of HPC as an outstanding drug carrier system.

 

Key words: hollow polymer capsules, drug delivery, methodology, 2D materials

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