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General Chemistry ›› 2018, Vol. 4 ›› Issue (2): 180014-180014.DOI: 10.21127/yaoyigc20180014

• Minireviews • Previous Articles     Next Articles

Nanomaterial Fused Monolithic Microcolumns for Biomolecule Separation

M. A. Vijayalakshmi, Kishore K. R. Tetala()   

  1. Advanced Centre for Bioseparation Technology, Vellore Institute of Technology, Vellore, Tamil Nadu-632014, India
  • Received:2018-05-11 Accepted:2018-06-17 Online:2018-06-27 Published:2018-06-27
  • Contact: Kishore K. R. Tetala

Abstract: Achieving a highly pure biomolecule of interest is of great importance and chromatography based techniques are the reliable tools for this challenging task. During the last few decades, monoliths have been explored as alternative chromatography stationary phases for biomolecule separation. In this Minireview, we aim to provide information on different nanomaterials incorporated within the network of monoliths and strategies applied to perform nanomaterial surface  functionalization. Subsequently, the applications of “nanomaterials embedded monolithic microcolumns” for separation of target biomolecules such as proteins and peptides with the help of different chromatography principles such as affinity, ionic and hydrophobic is also discussed in detail.

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