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General Chemistry ›› 2018, Vol. 4 ›› Issue (1): 170019-170019.DOI: 10.21127/yaoyigc20170019

• Minireviews •     Next Articles

Magnetic Resonance Switch for Biological Detection

Chenglin Yan, Qiwei Tian*()   

  1. Key Laboratory of Resource Chemistry of Ministry of Education, Shanghai Key Laboratory of Rare Earth Functional Materials, and Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors, Shanghai Normal University, Shanghai 200234, China
  • Received:2017-11-06 Accepted:2018-03-06 Online:2018-03-21 Published:2018-03-21
  • Supported by:
     

Abstract:

Magnetic nanoparticles (MNPs) possess great potential in biological applications, especially as a highly useful tool or contrast agents for clinical diagnosis and disease monitoring in magnetic resonance imaging. When external magnetic field is introduced, the local magnetic field inhomogeneity caused by magnetization of MNPs can induce the change of relaxation for realizing the imaging. Therefore, rational design of magnetic relaxation switches sensors capable of biological detection has been a major goal in the advancement of clinical application. In this minireview, we summarize some advances on magnetic sensors, involving in sensing principles of MNPs and biological applications of magnetic sensors; moreover, we collect important and up-to-date information, which may help to develop the method of obtaining high performance magnetic sensors, especially for biological application.

 

Key words: magnetic resonance sensors, magnetic nanoparticles, single model, bi-model

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